Protein Details: Glycine receptor subunit alpha-1

Protein ID

ICDB_Pro_1060

Protein Name

Glycine receptor subunit alpha-1

Gene Name

Glra1

Organism

Mus musculus (Mouse)

Length

457 amino acids

AlphaFoldDB

AF-Q64018-F1-model_v4.pdb

Function

Sequence

MYSFNTLRFYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

220;222;230-235;243;289

Disease

Location

Detected in spinal cord neurons.Detected in brain stem neurons.Detected at lower levels in hippocampus and cerebellum. Detected in the inner plexiform layer of the retina (at protein level).